I guide peri-menopausal women to overcome inflammation and brain fog, optimize mental clarity, achieve life changing weight loss and experience vibrant energy and vitality.

Rana Mafee, MD

I guide peri-menopausal women to overcome inflammation and brain fog, optimize mental clarity, achieve life changing weight loss and experience vibrant energy and vitality.

Rana Mafee, MD

Areas of Expertise

  • Medical school graduate from Rush University

  • Residency and fellowship trainings at the University of Chicago, University of Iowa and University of Illinois

  • Board certified in neurology and integrative medicine

  • Trained in Acupuncture at the Helms Medical Institute

  • Fully trained in functional medicine by the Institute for Functional Medicine

  • A Recode certified practitioner for preventing and reversing cognitive decline

  • Over a decade long student of yoga

Dr. Rana works closely, guiding and coaching clients wanting to transform their health and their lives. After over 10 years as a medical doctor, Dr. Rana overhauled her practice and spent the next 10 years incorporating integrative and functional medicine in the clinic. Years of treating patients in a holistic and systems based fashion made one thing clear. Outcomes are far more exceptional with this approach. And outcomes are even far more exceptional when patients make the necessary therapeutic, sustainable and lasting lifestyle changes. She also observed that this was most likely to occur when there was explicit guidance and hand holding all along the way. This was most evident in her work with patients on the spectrum of cognitive decline using the Recode Protocol. It is her mission now to be the guide and change agent to help facilitate health and life transformations for as many people as possible.

My Story

In my early years as a practicing neurologist, I found myself often longing for more solutions outside of my prescription pad for my patients. Personally, I was also silently suffering with autoimmune and digestive conditions of my own. I had curiosities about complementary and alternative strategies and tried some unsuccessfully for me and my patients. Then I discovered integrative medicine. After attending my first conference, I was hooked, and dove head first into reinventing my practice.

Shortly after studying integrative medicine, I trained in functional medicine as well. My primary intention was to be able to deliver more tools to my patients, but what I did not expect was how profoundly I ultimately made an impact on my own health. After making lasting and impactful lifestyle changes, autoimmune issues either stabilized or disappeared. Chronic irritable bowel syndrome became a thing of the past. I was experiencing much improved energy, focus and mood.

All the while, I was witnessing profound transformations in my practice as well. A patient with debilitating multiple sclerosis was able to reduce her pain medications and need for mobility devices, allowing her to not only walk but exercise again and experience vastly improved energy.

A 20 year old woman with lifelong attention deficit disorder and disabling depression who was unable to successfully attend college was able to lift her depression and improve her focus allowing her to be able to enroll as a successful student.

A woman in her 40s with debilitating fibromyalgia, chronic daily headaches and depression was able to lose 75 pounds, come off depression medications and significantly reduce her body-wide pain and migraines.

The most profound observations that I made though were in those suffering with cognitive issues, especially after certifying in and applying the Recode Protocol. I observed that certain fundamental factors were at play especially in middle aged women experiencing cognitive difficulties. Hormonal concerns, metabolic issues, blood sugar imbalance, inflammation and weight gain were central factors. What this solidified for me most is that lifestyle medicine really is where the magic happens. And observing how challenging it could be for patients to apply these principles without expert, close and laser focused guidance drove me to where I am today, intending to be that guide for clients to achieve those life transformations.

If you are struggling to lose weight, eliminate chronic inflammation and fatigue, and balance your hormones, know that there are evidence based integrative answers. Especially if you are dealing with brain fog or cognitive issues, know that there are solid solutions. If this is you, feel free to connect with me, and definitely get your free Harmonize Your Hormones Starter Kit. Major transformations do occur from consistent minor changes!

Dr. Rana works closely with clients through telemedicine, using a functional medicine model

to address your overall health in a unique, holistic/systems oriented and root cause approach. This is an intensive way to approach chronic health conditions - in opposition to how you would normally experience through a more conventional 'cookbook' approach.

The goal is to provide exceptional and transformative health solutions to those who seek guidance and care!

As Seen On

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Harmonize Your Hormones Starter Kit Includes

  • Harmonize Your Hormones Quiz

A diagnostic quiz designed to help you assess metabolic & hormone balance & brain health.

  • 8 Tips To Balanced Hormones, A Trimmer Waist, & Mental Clarity

Everything you need to be on a path to optimal metabolism, digestion, brain health, and getting off the hormonal roller coaster.

  • 7 Day Healthy Habit Tracker

A behavioral tool to help keep you on track!

Testimonials

Jen M.

Early in 2024, I found myself not recovering from a recent Covid infection. A friend connected me with Dr. Rana Mafee and I have been working with her for the past five months. Dr. Rana has been an invaluable resource as I work to improve my health. She is knowledgable about the most current research, data and treatment protocols. She considers all your life domains when developing your treatment plan. She looked at me as a whole person and created specific treatment protocols for my health goals. She and I worked to improve my nutrition, energy, sleep and so much more. She is a caring, understanding and thorough Dr who is passionate about improving her client's health and well-being. I would whole-heartedly recommend Dr. Rana for those looking to improve health and quality of life!

Amanda M.

I am forever grateful for participating in Dr. Rana’s 12 week ENRG program. She opened my mind to a different approach and perspective to my health management and made a huge healthy lifestyle transition a reality for me. There is a lot of information to absorb during the 12 weeks and she set up the program at a good pace for any type of individual to be successful on their journey.

I feel I now have the right tools to make the day to day decisions that are best for my mind, body, and soul. I really appreciated her compassion for the medical journey I had been on. It was the first time in years I felt a medical professional was actively listening to me and truly cared about looking at the whole picture. She always gave me really thoughtful advice and was always willing to answer any question that came up for me. We addressed obstacles that came up in real time and she really helped me navigate some challenging setbacks. I am a very complex case and she never made made me feel like a “complicated patient” as so many physicians have made me feel before. She always went and above and beyond to understand in detail the symptoms I experience and how to reverse them instead of put a band aid on the source of the issue. My entire outlook on what I put in, on, and around my body has changed for the better. This information should be common knowledge but unfortunately is not.

Dr. Rana shares all of her knowledge and advice but is not at all pushy like so many people often are. She never comes from a place of judgement, only

compassion and education to help me reach my goals. I am proud of myself for starting my journey to a better quality life with Dr. Rana and I will recommend that anyone seeking a healthy change in their life embark on this program. We are all faced with so many options each day and this program helps you make the right choices to live an energized, good quality life. Be an advocate for your health and start the journey with Dr. Rana!!

Monica B.


My name is Monica and I’m a 55-year-old, married mother of three. I’d been struggling with pain for a couple years when I was introduced to Dr. Rana. I first noticed the pain in my joints, caused by obvious inflammation in the knuckles of my hands. I also experienced severe stomach pain, hot flashes and headaches, making it almost impossible for me to sleep most nights. I saw numerous doctors, including my primary care physician, two gastroenterologists, two rheumatologists and a neurologist, seeking relief. I even had my gall bladder removed based on the belief that may be causing my stomach pain. As you will see below, I’m now questioning that decision. Most recently, I was diagnosed with rheumatoid arthritis. With the prospect of taking a prescription mediation for the rest of my life, I sought a second opinion and was told my diagnosis was unclear at best and to hold off on undergoing treatment for rheumatoid arthritis. At that point I was extremely confused and at a loss for what to do next.

By chance, I shared my story with a close friend who is a physician and was unaware of my ordeal. She urged me to consider calling Dr. Rana and I am so glad I did!   Meeting with Dr. Rana virtually, she listened intently to my story and thoroughly examined my medical history. She asked me questions that other doctors had not asked in an attempt to identify the possible source of my pain. Dr. Rana also assigned weekly homework in the form of watching her educational videos, each one like watching an episode of Masterclass – they are incredibly well-done and extremely informative. These videos really helped me get more educated about functional medicine.   Ultimately, Dr. Rana suggested I consider cutting out of my diet a few foods that may be causing inflammation. I must admit, it was a shock to the system, but I was totally committed to do anything I could to find relief. Dr. Rana helped me understand that many of my health issues may be the result of my gut health.

Over time I slowly added back some but have permanently cut out certain foods that I believe may have contributed to my inflammation and pain. I also began taking supplements because Dr. Rana suggested I may be lacking certain essential vitamins.   Having now completed Dr. Rana’s 12-week program, I can honestly say I’ve seen dramatic improvement! My joint pain is minimal, I’m even back to playing tennis twice a week, I rarely have headaches, stomach pain or hot flashes. Before Dr. Rana I could count on one hand the number of nights I was able to sleep through the night without waking up in pain. Now, I sleep comfortably through the night on a regular basis. It’s really amazing the progress I’ve made in a relatively short period of time. I feel more energetic now than I have for years and have a completely new outlook on my health and well-being.  

I have already recommended Dr. Rana to a number of my friends and will continue to recommend her to anyone feeling the same helplessness I did about my health situation. She is so easy to talk to, very knowledgeable, responsive and supportive. To say her advice and recommendations were effective would be a total understatement; working with Dr. Rana was life-changing! The only person I may be more grateful for is my friend who had the forethought to recommend I get in touch with Dr. Rana in the first place.

Tracy N.

I’ve had multiple sclerosis for over 20 years, eventually as a primary progressive form. I had lost hope for several years, being reliant on my assistive devices and too tired and fatigued and in a fog to do much of anything. I stumbled on the Wahls Protocol but did not know where to begin and hesitated as I thought chances were slim I could turn anything around. After finding Dr. Rana, I was still skeptical, but I gave her program a shot since she seemed to have all the qualifications I was looking for. It took some educating, guiding, coaching and perseverance but I completely changed my diet and some of my lifestyle habits and incorporated some targeted supplements she recommended. Within just a month, I lost 8 pounds, started to notice significantly improved energy and was able to walk with my cane in my neighborhood with my family! Family and friends also noticed I seemed less foggy and more clear. After another month, things started to continue to improve even more. I can walk short distances without my cane, I have so much more energy and my digestion is improved too! I’m a true believer now and will forever be thankful for my experience with Dr. Rana! She is so knowledgeable, dedicated to my success and compassionate. Don’t hesitate to sign up for her program!

Nikki B.


When I started working with Dr. Rana, my health was at an all time low.  I was a newish mom, working long hours and in the never-ending cycle of viruses from my kids daycare. Sleep was terrible or non-existent, which then resulted in lots of stress and overall poor health.  There would be days where my mood would be so low that each day would be an emotional struggle.  I hated the way I felt and knew that a lot of things needed to change, I just didn’t know what or how to change them because it all felt very overwhelming.  

I was concerned initially that I would not be able to successfully go through the program and make the changes.  My personal life and my career are insanely busy.  My career is very unpredictable and riddled with very stressful moments.  Dr. Rana’s program was a welcomed escape and positive part of my hectic day.  The program is very conducive to someone who is busy.  Everything is broken down and so well organized that it never felt overwhelming and always seemed manageable.  As I began to notice changes, I looked forward to the next challenge because I had reinforcement that what she had to say made sense and worked!  

The first thing I noticed was that I was able to curb my cravings for all things sweet!  This was a big thing for me, because I felt like I always had to have them.  The more I learned about nutrition, the more I wanted to control what goes in my body and ensure it was healthy foods as opposed to processed sugar. I wasn’t even intentionally committing to cutting out sweets, it just organically happened the more I leavened and the more I began to fill my belly with healthy foods!  This turned into weight loss.  I was shocked when I weighed myself and realized I lost weight because again, my main goal was just to be healthy, happy and have more energy.  As I continued working with Dr. Rana, I began noticing more energy and my mood improved. I began to notice a pattern related to my mood and my menstrual cycle.  During the focus on hormones, everything began to make sense and Dr. Rana was able to recommend some natural supplements that almost immediately helped.  I noticed my mood improved and my belly fat began to disappear!  

The best part of getting the positive results was the added benefit of me being able to be more active and present with my kiddos! When I started this program I was so sad that I wasn’t being the best mom I could be to my kids and was not modeling a healthy lifestyle.  This program changed all of this and had actually helped me to incorporate healthy habits for my kiddos!  

Being coached by Dr. Rana was like having an expert doctor, friend, counselor and cheerleader all in one!  It’s very evident that she has passion for what she does and genuinely cares about the well-being of her patients/clients.  Dr. Rana is absolutely brilliant and knows her stuff! Obviously that is crucial when you are trying to make lifestyle changes that can be challenging at times because you want the confidence that what you are being told is actually safe and backed by science.  Beyond her knowledge, Dr. Rana is caring and compassionate.  She genuinely cares about helping people and educating people on how to live a healthy life in every aspect.  I was very honest about things that were hard for me to talk about, and Dr. Rana always listened and was never judgmental.  She offered understanding, empathy and gave me tools to improve whatever it was I was struggling with. I would tell anyone that if you want to make actual changes in your life, following this program and being coached by Dr. Rana will do that.  You have to put in the work, but I promise you, it WILL work!  Life is too short to be spent feeling less than your best!  

Naomi R.

An acquaintance of mine who saw Dr. Rana as a patient a few years ago referred me to her program for a new diagnosis of alopecia areata. I was so devastated by all the hair loss and stress from my condition. Having gotten a strong endorsement from someone, I signed up to work with her. Although my hair growth recovery was not immediate, I had tremendous success during her 12 week program! Not only did I recover hair growth, but I lost a total of 28 pounds! I had no idea the impact my diet was having on my body and all the inflammation it was causing. In fact I had tried for years to lose weight in weight loss programs unsuccessfully. I was even told I was pre-diabetic by my doctor in recent years and urged to start medication, but I hesitated. After going through this program, I now realize how important reducing the inflammation and addressing my gut health was to reverse the prediabetes and finally achieve weight loss. I am forever in debt to Dr. Rana! I’m almost in complete remission from alopecia areata too! Woo hoo!

Juliet S.

Working with Dr. Rana has changed my life! I started working with her hoping to lose 5 pounds (thinking it would be impossible to lose any more than that given that I am in perimenopause) and balance my hormones. I ended up losing 15 pounds by after 12 weeks, reduced my stress levels, and went from having moderate to severe PMS symptoms (cramping, heavy flow, taking ibuprofen consistently during my period) to having virtually no PMS symptoms. In addition, my mood is improved, my focus is enhanced, I rarely get headaches now, and I feel mentally sharper. I am more efficient at work, and I am much more mindful in my daily life. I feel the best I've ever felt, both mentally and physically. I learned new habits that will stick with me for a lifetime. Her holistic and supportive approach is incredibly effective, and I highly recommend Dr. Rana to anyone who is looking for a comprehensive means to improve all facets of wellness!

Natalie E.

I’m in my late 40s and was starting to really feel the perimenopause kick in. My sleep was horrible, I was an anxious mess, and my cycles were all over the place. Worst of all, I was feeling like I was losing my memory and was so worried I was heading towards dementia. My gynecologist suggested I start hormone replacement, but I was so hesitant as I was so confused by it all. I stumbled on Dr. Rana’s program, and I decided to try this first before jumping to hormones. I needed to lose weight, and my diet was terrible (now I realize that even though I thought I was eating “healthy”!). It was also SO difficult to lose the weight, especially the belly fat in my later 40s. I learned a lot about why that is as I was going through the program and how to overcome it finally. Within the first month of making some lifestyle changes and starting some supplements she recommended, I started to notice a real change. Better sleep, less anxiety, a smoother cycle, and I felt the brain fog finally starting to lift. By 3 months, I was so much more relaxed and mentally clear, and I had lost 15 pounds! Belly fat gone! My cycles are not perfect, but so much better and no longer having heavy and painful periods. I know I am heading towards menopause, but I have so many tools now to be able to deal with the changes! I may need hormones down the line and feel more at ease about my future decisions about it, as Dr. Rana clearly explains the science and applications of it. Thank you Dr. Rana!

Have a question?

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